DNA-like class R inhibitory oligonucleotides (INH-ODNs) preferentially block autoantigen-induced B-cell and dendritic cell activation in vitro and autoantibody production in lupus-prone MRL-Fas(lpr/lpr )mice in vivo

INTRODUCTION: B cells have many different roles in systemic lupus erythematosus (SLE), ranging from autoantigen recognition and processing to effector functions (for example, autoantibody and cytokine secretion). Recent studies have shown that intracellular nucleic acid-sensing receptors, Toll-like...

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Detalles Bibliográficos
Autores principales: Lenert, Petar, Yasuda, Kei, Busconi, Liliana, Nelson, Patrice, Fleenor, Courtney, Ratnabalasuriar, Radhika S, Nagy, Peter L, Ashman, Robert F, Rifkin, Ian R, Marshak-Rothstein, Ann
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714127/
https://www.ncbi.nlm.nih.gov/pubmed/19476613
http://dx.doi.org/10.1186/ar2710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714127/
https://www.ncbi.nlm.nih.gov/pubmed/19476613
http://dx.doi.org/10.1186/ar2710

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