Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study

INTRODUCTION: Aggrecanase cleavage at the (392)Glu-(393)Ala bond in the interglobular domain (IGD) of aggrecan, releasing N-terminal (393)ARGS fragments, is an early key event in arthritis and joint injuries. Here, we use a quantitative immunoassay of aggrecan ARGS neoepitope fragments in human syno...

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Detalles Bibliográficos
Autores principales: Larsson, Staffan, Lohmander, L Stefan, Struglics, André
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714148/
https://www.ncbi.nlm.nih.gov/pubmed/19545413
http://dx.doi.org/10.1186/ar2735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714148/
https://www.ncbi.nlm.nih.gov/pubmed/19545413
http://dx.doi.org/10.1186/ar2735

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