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Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer

BACKGROUND: As negative regulators in Wnt signaling, Secreted Frizzled-Related Proteins (SFRPs) are downregulated in a series of human cancers; and specifically, some matrix metalloproteinases (MMPs), including MMP-2, MMP-7, MMP-9 and MT1-MMP, are frequently overexpressed in gastric cancer. The aim...

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Detalles Bibliográficos
Autores principales: Zhao, Chenghai, Bu, Xianmin, Zhang, Ning, Wang, Wei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714159/
https://www.ncbi.nlm.nih.gov/pubmed/19586554
http://dx.doi.org/10.1186/1471-2407-9-224