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Downregulation of SFRP5 expression and its inverse correlation with those of MMP-7 and MT1-MMP in gastric cancer

BACKGROUND: As negative regulators in Wnt signaling, Secreted Frizzled-Related Proteins (SFRPs) are downregulated in a series of human cancers; and specifically, some matrix metalloproteinases (MMPs), including MMP-2, MMP-7, MMP-9 and MT1-MMP, are frequently overexpressed in gastric cancer. The aim...

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Detalles Bibliográficos
Autores principales:	Zhao, Chenghai, Bu, Xianmin, Zhang, Ning, Wang, Wei
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714159/ https://www.ncbi.nlm.nih.gov/pubmed/19586554 http://dx.doi.org/10.1186/1471-2407-9-224

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