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Glucocorticoid resistance in T-lineage acute lymphoblastic leukaemia is associated with a proliferative metabolism

Glucocorticoids (GCs) are among the most important drugs for acute lymphoblastic leukaemia (ALL), yet despite their clinical importance, the exact mechanisms involved in GC cytotoxicity and the development of resistance remain uncertain. We examined the baseline profile of a panel of T-ALL cell line...

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Detalles Bibliográficos
Autores principales: Beesley, A H, Firth, M J, Ford, J, Weller, R E, Freitas, J R, Perera, K U, Kees, U R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714233/
https://www.ncbi.nlm.nih.gov/pubmed/19436302
http://dx.doi.org/10.1038/sj.bjc.6605072