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HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells

HuR, a ubiquitously expressed member of the Hu protein family that binds and stabilizes an AU-rich element (ARE)-containing mRNAs, is known to shuttle between the nucleus and the cytoplasm via several export pathways. When normal cells were treated with heat shock, HuR was exported to the cytoplasm...

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Detalles Bibliográficos
Autores principales: Hasegawa, H, Kakuguchi, W, Kuroshima, T, Kitamura, T, Tanaka, S, Kitagawa, Y, Totsuka, Y, Shindoh, M, Higashino, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714239/
https://www.ncbi.nlm.nih.gov/pubmed/19513080
http://dx.doi.org/10.1038/sj.bjc.6605084