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Nuclear accumulation of polyglutamine disease proteins and neuropathology

There are nine inherited neurodegenerative disorders caused by polyglutamine (polyQ) expansion in various disease proteins. Although these polyglutamine proteins have different functions and are localized in different subcellular regions, all the polyQ diseases share a common pathological feature: t...

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Detalles Bibliográficos
Autores principales: Havel, Lauren S, Li, Shihua, Li, Xiao-Jiang
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714308/
https://www.ncbi.nlm.nih.gov/pubmed/19575804
http://dx.doi.org/10.1186/1756-6606-2-21