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Nuclear accumulation of polyglutamine disease proteins and neuropathology
There are nine inherited neurodegenerative disorders caused by polyglutamine (polyQ) expansion in various disease proteins. Although these polyglutamine proteins have different functions and are localized in different subcellular regions, all the polyQ diseases share a common pathological feature: t...
Autores principales: | Havel, Lauren S, Li, Shihua, Li, Xiao-Jiang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714308/ https://www.ncbi.nlm.nih.gov/pubmed/19575804 http://dx.doi.org/10.1186/1756-6606-2-21 |
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