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The Del1 deposition domain can immobilize 3α-hydroxysteroid dehydrogenase in the extracellular matrix without interfering with enzymatic activity

Developing methods that result in targeting of therapeutic molecules in gene therapies to target tissues has importance, as targeting can increase efficacy and decrease off target-side-effects. Work from my laboratory previously showed that the extracellular matrix protein Del1 is organized in the e...

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Detalles Bibliográficos
Autores principales: Hidai, Chiaki, Kitano, Hisataka, Kokubun, Shinichiro
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714445/
https://www.ncbi.nlm.nih.gov/pubmed/19018576
http://dx.doi.org/10.1007/s00449-008-0278-5