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Evaluation of RTS,S/AS02A and RTS,S/AS01B in Adults in a High Malaria Transmission Area

BACKGROUND: This study advances the clinical development of the RTS,S/AS01B candidate malaria vaccine to malaria endemic populations. As a primary objective it compares the safety and reactogenicity of RTS,S/AS01B to the more extensively evaluated RTS,S/AS02A vaccine. METHODOLOGY: A Phase IIb, singl...

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Detalles Bibliográficos
Autores principales: Polhemus, Mark E., Remich, Shon A., Ogutu, Bernhards R., Waitumbi, John N., Otieno, Lucas, Apollo, Stella, Cummings, James F., Kester, Kent E., Ockenhouse, Christian F., Stewart, Ann, Ofori-Anyinam, Opokua, Ramboer, Isabelle, Cahill, Conor P., Lievens, Marc, Dubois, Marie-Claude, Demoitie, Marie-Ange, Leach, Amanda, Cohen, Joe, Ballou, W. Ripley, Heppner,, D. Gray
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714466/
https://www.ncbi.nlm.nih.gov/pubmed/19649245
http://dx.doi.org/10.1371/journal.pone.0006465