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Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF)

Chlorpyrifos (CPF) is a pesticide that causes tens of thousands of deaths per year worldwide. Chlorpyrifos oxon (CPO) is the active metabolite of CPF that inhibits acetylcholinesterase. However, this presumed metabolite has escaped detection in human samples by conventional methods (HPLC, GC-MS, LC-...

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Detalles Bibliográficos
Autores principales: Eyer, Florian, Roberts, Darren M., Buckley, Nicholas A., Eddleston, Michael, Thiermann, Horst, Worek, Franz, Eyer, Peter
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714474/
https://www.ncbi.nlm.nih.gov/pubmed/19433070
http://dx.doi.org/10.1016/j.bcp.2009.05.004