Regulation of TGF-β signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant

BACKGROUND: Jeff is a dominant mouse mutant displaying chronic otitis media. The gene underlying Jeff is Fbxo11, a member of the large F-box family, which are specificity factors for the SCF E3 ubiquitin ligase complex. Jeff homozygotes die shortly after birth displaying a number of developmental ab...

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Detalles Bibliográficos
Autores principales: Tateossian, Hilda, Hardisty-Hughes, Rachel E, Morse, Susan, Romero, Maria R, Hilton, Helen, Dean, Charlotte, Brown, Steve DM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714483/
https://www.ncbi.nlm.nih.gov/pubmed/19580641
http://dx.doi.org/10.1186/1755-8417-2-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714483/
https://www.ncbi.nlm.nih.gov/pubmed/19580641
http://dx.doi.org/10.1186/1755-8417-2-5

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