Cargando…

Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia

BACKGROUND: The regulation of protein phosphorylation requires a balance in the activity of protein kinases and protein phosphatases. Our previous data indicates that Src can increase ERK activity through Raf kinase in response to ischemic stimuli. This study examined the molecular mechanisms by whi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Xiaohan, Wu, Xiangyang, Xu, Jiali, Zhou, Jin, Han, Xiao, Guo, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714518/
https://www.ncbi.nlm.nih.gov/pubmed/19602257
http://dx.doi.org/10.1186/1471-2202-10-74