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TNF-α-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells

BACKGROUND: Phosphatidylcholine (PC) is a major lipid of the gastrointestinal mucus layer. We recently showed that mucus from patients suffering from ulcerative colitis has low levels of PC. Clinical studies reveal that the therapeutic addition of PC to the colonic mucus using slow release preparati...

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Detalles Bibliográficos
Autores principales: Treede, Irina, Braun, Annika, Jeliaskova, Petia, Giese, Thomas, Füllekrug, Joachim, Griffiths, Gareth, Stremmel, Wolfgang, Ehehalt, Robert
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714528/
https://www.ncbi.nlm.nih.gov/pubmed/19594939
http://dx.doi.org/10.1186/1471-230X-9-53