Cargando…
TNF-α-induced up-regulation of pro-inflammatory cytokines is reduced by phosphatidylcholine in intestinal epithelial cells
BACKGROUND: Phosphatidylcholine (PC) is a major lipid of the gastrointestinal mucus layer. We recently showed that mucus from patients suffering from ulcerative colitis has low levels of PC. Clinical studies reveal that the therapeutic addition of PC to the colonic mucus using slow release preparati...
Autores principales: | Treede, Irina, Braun, Annika, Jeliaskova, Petia, Giese, Thomas, Füllekrug, Joachim, Griffiths, Gareth, Stremmel, Wolfgang, Ehehalt, Robert |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714528/ https://www.ncbi.nlm.nih.gov/pubmed/19594939 http://dx.doi.org/10.1186/1471-230X-9-53 |
Ejemplares similares
-
Lipid Based Therapy for Ulcerative Colitis—Modulation of Intestinal Mucus Membrane Phospholipids as a Tool to Influence Inflammation
por: Schneider, Hannah, et al.
Publicado: (2010) -
Overexpression of CD36 and Acyl-CoA Synthetases FATP2, FATP4 and ACSL1 Increases Fatty Acid Uptake in Human Hepatoma Cells
por: Krammer, Julia, et al.
Publicado: (2011) -
Transcript levels of different cytokines and chemokines correlate with clinical and endoscopic activity in ulcerative colitis
por: Zahn, Alexandra, et al.
Publicado: (2009) -
Uptake of long chain fatty acids is regulated by dynamic interaction of FAT/CD36 with cholesterol/sphingolipid enriched microdomains (lipid rafts)
por: Ehehalt, Robert, et al.
Publicado: (2008) -
Outlook: membrane junctions enable the metabolic trapping of fatty acids by intracellular acyl-CoA synthetases
por: Füllekrug, Joachim, et al.
Publicado: (2012)