Talin Phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitination and cell migration

Cell migration is a dynamic process that requires temporal and spatial regulation of integrin activation and focal adhesion assembly-disassembly1. Talin, an actin and β integrin tail-binding protein, is essential for integrin activation and focal adhesion formation2,3. Calpain-mediated cleavage of t...

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Detalles Bibliográficos
Autores principales: Huang, Cai, Rajfur, Zenon, Yousefi, Nima, Chen, Zaozao, Jacobson, Ken, Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714540/
https://www.ncbi.nlm.nih.gov/pubmed/19363486
http://dx.doi.org/10.1038/ncb1868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714540/
https://www.ncbi.nlm.nih.gov/pubmed/19363486
http://dx.doi.org/10.1038/ncb1868

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