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Talin Phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitination and cell migration
Cell migration is a dynamic process that requires temporal and spatial regulation of integrin activation and focal adhesion assembly-disassembly1. Talin, an actin and β integrin tail-binding protein, is essential for integrin activation and focal adhesion formation2,3. Calpain-mediated cleavage of t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714540/ https://www.ncbi.nlm.nih.gov/pubmed/19363486 http://dx.doi.org/10.1038/ncb1868 |