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In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

BACKGROUND: The transcription factor OCT4 is highly expressed in pluripotent embryonic stem cells which are derived from the inner cell mass of mammalian blastocysts. Pluripotency and self renewal are controlled by a transcription regulatory network governed by the transcription factors OCT4, SOX2 a...

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Detalles Bibliográficos
Autores principales: Chavez, Lukas, Bais, Abha S, Vingron, Martin, Lehrach, Hans, Adjaye, James, Herwig, Ralf
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714862/
https://www.ncbi.nlm.nih.gov/pubmed/19604364
http://dx.doi.org/10.1186/1471-2164-10-314