Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

We recently developed a novel strategy to identify transmitted HIV-1 genomes in acutely infected humans using single-genome amplification and a model of random virus evolution. Here, we used this approach to determine the molecular features of simian immunodeficiency virus (SIV) transmission in 18 e...

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Detalles Bibliográficos
Autores principales: Keele, Brandon F., Li, Hui, Learn, Gerald H., Hraber, Peter, Giorgi, Elena E., Grayson, Truman, Sun, Chuanxi, Chen, Yalu, Yeh, Wendy W., Letvin, Norman L., Mascola, John R., Nabel, Gary J., Haynes, Barton F., Bhattacharya, Tanmoy, Perelson, Alan S., Korber, Bette T., Hahn, Beatrice H., Shaw, George M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715022/
https://www.ncbi.nlm.nih.gov/pubmed/19414559
http://dx.doi.org/10.1084/jem.20082831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715022/
https://www.ncbi.nlm.nih.gov/pubmed/19414559
http://dx.doi.org/10.1084/jem.20082831

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