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IL-4–producing CD4(+) T cells in reactive lymph nodes during helminth infection are T follicular helper cells
Interleukin (IL)-4 is the quintessential T helper type 2 (Th2) cytokine produced by CD4(+) T cells in response to helminth infection. IL-4 not only promotes the differentiation of Th2 cells but is also critical for immunoglobulin (Ig) G1 and IgE isotype-switched antibody responses. Despite the IL-4–...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715031/ https://www.ncbi.nlm.nih.gov/pubmed/19380638 http://dx.doi.org/10.1084/jem.20090313 |