Ikaros controls isotype selection during immunoglobulin class switch recombination

Class switch recombination (CSR) allows the humoral immune response to exploit different effector pathways through specific secondary antibody isotypes. However, the molecular mechanisms and factors that control immunoglobulin (Ig) isotype choice for CSR are unclear. We report that deficiency for th...

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Detalles Bibliográficos
Autores principales: Sellars, MacLean, Reina-San-Martin, Bernardo, Kastner, Philippe, Chan, Susan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715033/
https://www.ncbi.nlm.nih.gov/pubmed/19414557
http://dx.doi.org/10.1084/jem.20082311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715033/
https://www.ncbi.nlm.nih.gov/pubmed/19414557
http://dx.doi.org/10.1084/jem.20082311

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