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Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13–induced tissue responses and apoptosis

Mouse breast regression protein 39 (BRP-39; Chi3l1) and its human homologue YKL-40 are chitinase-like proteins that lack chitinase activity. Although YKL-40 is expressed in exaggerated quantities and correlates with disease activity in asthma and many other disorders, the biological properties of BR...

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Detalles Bibliográficos
Autores principales: Lee, Chun Geun, Hartl, Dominik, Lee, Gap Ryol, Koller, Barbara, Matsuura, Hiroshi, Da Silva, Carla A., Sohn, Myung Hyun, Cohn, Lauren, Homer, Robert J., Kozhich, Alexander A., Humbles, Alison, Kearley, Jennifer, Coyle, Anthony, Chupp, Geoffrey, Reed, Jennifer, Flavell, Richard A., Elias, Jack A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715037/
https://www.ncbi.nlm.nih.gov/pubmed/19414556
http://dx.doi.org/10.1084/jem.20081271