Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum

Threats of bioterrorism have renewed efforts to better understand poxvirus pathogenesis and to develop a safer vaccine against smallpox. Individuals with atopic dermatitis are excluded from smallpox vaccination because of their propensity to develop eczema vaccinatum, a disseminated vaccinia virus (...

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Detalles Bibliográficos
Autores principales: Kawakami, Yuko, Tomimori, Yoshiaki, Yumoto, Kenji, Hasegawa, Shunji, Ando, Tomoaki, Tagaya, Yutaka, Crotty, Shane, Kawakami, Toshiaki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715052/
https://www.ncbi.nlm.nih.gov/pubmed/19468065
http://dx.doi.org/10.1084/jem.20082835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715052/
https://www.ncbi.nlm.nih.gov/pubmed/19468065
http://dx.doi.org/10.1084/jem.20082835

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