Milk fat globule epidermal growth factor–8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms

Carcinogenesis reflects the dynamic interplay of transformed cells and normal host elements, but cancer treatments typically target each compartment separately. Within the tumor microenvironment, the secreted protein milk fat globule epidermal growth factor–8 (MFG-E8) stimulates disease progression...

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Detalles Bibliográficos
Autores principales: Jinushi, Masahisa, Sato, Marimo, Kanamoto, Akira, Itoh, Akihiko, Nagai, Shigenori, Koyasu, Shigeo, Dranoff, Glenn, Tahara, Hideaki
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715055/
https://www.ncbi.nlm.nih.gov/pubmed/19433619
http://dx.doi.org/10.1084/jem.20082614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715055/
https://www.ncbi.nlm.nih.gov/pubmed/19433619
http://dx.doi.org/10.1084/jem.20082614

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