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Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions
Many human genes have adapted to the constant threat of exposure to infectious agents; according to the “hygiene hypothesis,” lack of exposure to parasites in modern settings results in immune imbalances, augmenting susceptibility to the development of autoimmune and allergic conditions. Here, by es...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715056/ https://www.ncbi.nlm.nih.gov/pubmed/19468064 http://dx.doi.org/10.1084/jem.20082779 |