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Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

Many human genes have adapted to the constant threat of exposure to infectious agents; according to the “hygiene hypothesis,” lack of exposure to parasites in modern settings results in immune imbalances, augmenting susceptibility to the development of autoimmune and allergic conditions. Here, by es...

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Detalles Bibliográficos
Autores principales: Fumagalli, Matteo, Pozzoli, Uberto, Cagliani, Rachele, Comi, Giacomo P., Riva, Stefania, Clerici, Mario, Bresolin, Nereo, Sironi, Manuela
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715056/
https://www.ncbi.nlm.nih.gov/pubmed/19468064
http://dx.doi.org/10.1084/jem.20082779