Zinc transporter Znt5/Slc30a5 is required for the mast cell–mediated delayed-type allergic reaction but not the immediate-type reaction

Zinc (Zn) is an essential nutrient and its deficiency causes immunodeficiency. However, it remains unknown how Zn homeostasis is regulated in mast cells and if Zn transporters are involved in allergic reactions. We show that Znt5/Slc30a5 is required for contact hypersensitivity and mast cell–mediate...

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Detalles Bibliográficos
Autores principales: Nishida, Keigo, Hasegawa, Aiko, Nakae, Susumu, Oboki, Keisuke, Saito, Hirohisa, Yamasaki, Satoru, Hirano, Toshio
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715059/
https://www.ncbi.nlm.nih.gov/pubmed/19451265
http://dx.doi.org/10.1084/jem.20082533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715059/
https://www.ncbi.nlm.nih.gov/pubmed/19451265
http://dx.doi.org/10.1084/jem.20082533

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