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Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity
There has long been conceptual and experimental support for, but also challenges to, the notion that the initial period of the immune system's development is particularly important for the establishment of tolerance to self. The display of self-antigens by thymic epithelial cells is key to indu...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715060/ https://www.ncbi.nlm.nih.gov/pubmed/19487417 http://dx.doi.org/10.1084/jem.20090300 |