Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

Hyper-IgE syndrome (HIES) is a primary immunodeficiency characterized by atopic manifestations and susceptibility to infections with extracellular pathogens, typically Staphylococcus aureus, which preferentially affect the skin and lung. Previous studies reported the defective differentiation of T h...

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Detalles Bibliográficos
Autores principales: Minegishi, Yoshiyuki, Saito, Masako, Nagasawa, Masayuki, Takada, Hidetoshi, Hara, Toshiro, Tsuchiya, Shigeru, Agematsu, Kazunaga, Yamada, Masafumi, Kawamura, Nobuaki, Ariga, Tadashi, Tsuge, Ikuya, Karasuyama, Hajime
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715068/
https://www.ncbi.nlm.nih.gov/pubmed/19487419
http://dx.doi.org/10.1084/jem.20082767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715068/
https://www.ncbi.nlm.nih.gov/pubmed/19487419
http://dx.doi.org/10.1084/jem.20082767

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