Normally occurring NKG2D(+)CD4(+) T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus

The NKG2D receptor stimulates natural killer cell and T cell responses upon engagement of ligands associated with malignancies and certain autoimmune diseases. However, conditions of persistent NKG2D ligand expression can lead to immunosuppression. In cancer patients, tumor expression and shedding o...

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Detalles Bibliográficos
Autores principales: Dai, Zhenpeng, Turtle, Cameron J., Booth, Garrett C., Riddell, Stanley R., Gooley, Theodore A., Stevens, Anne M., Spies, Thomas, Groh, Veronika
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715116/
https://www.ncbi.nlm.nih.gov/pubmed/19289577
http://dx.doi.org/10.1084/jem.20081648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715116/
https://www.ncbi.nlm.nih.gov/pubmed/19289577
http://dx.doi.org/10.1084/jem.20081648

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