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Netrin-1 acts as a survival factor for aggressive neuroblastoma

Neuroblastoma (NB), the most frequent solid tumor of early childhood, is diagnosed as a disseminated disease in >60% of cases, and several lines of evidence support the resistance to apoptosis as a prerequisite for NB progression. We show that autocrine production of netrin-1, a multifunctional l...

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Detalles Bibliográficos
Autores principales: Delloye-Bourgeois, Céline, Fitamant, Julien, Paradisi, Andrea, Cappellen, David, Douc-Rasy, Setha, Raquin, Marie-Anne, Stupack, Dwayne, Nakagawara, Akira, Rousseau, Raphaël, Combaret, Valérie, Puisieux, Alain, Valteau-Couanet, Dominique, Bénard, Jean, Bernet, Agnès, Mehlen, Patrick
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715117/
https://www.ncbi.nlm.nih.gov/pubmed/19349462
http://dx.doi.org/10.1084/jem.20082299