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The CUGBP2 Splicing Factor Regulates an Ensemble of Branchpoints from Perimeter Binding Sites with Implications for Autoregulation

Alternative pre-mRNA splicing adjusts the transcriptional output of the genome by generating related mRNAs from a single primary transcript, thereby expanding protein diversity. A fundamental unanswered question is how splicing factors achieve specificity in the selection of target substrates despit...

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Detalles Bibliográficos
Autores principales: Dembowski, Jill A., Grabowski, Paula J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715136/
https://www.ncbi.nlm.nih.gov/pubmed/19680430
http://dx.doi.org/10.1371/journal.pgen.1000595