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Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities
RAD51, a eukaryotic recombinase, catalyzes homologous-pairing and strand-exchange reactions, which are essential steps in homologous recombination and recombinational repair of double strand breaks. On the other hand, human PSF was originally identified as a component of spliceosomes, and its multip...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715225/ https://www.ncbi.nlm.nih.gov/pubmed/19447914 http://dx.doi.org/10.1093/nar/gkp298 |