CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA

CUGBP2 (ETR-3/NAPOR/BRUNOL3) promotes inclusion of cardiac troponin T (cTNT) exon 5 via binding between positions 21 and 74 of the downstream intron. The molecular mechanism by which CUGBP2 activates cTNT exon 5 inclusion is unknown. Our results suggest that CUGBP2 promotes exon inclusion by a novel...

Descripción completa

Detalles Bibliográficos
Autores principales: Goo, Young-Hwa, Cooper, Thomas A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715230/
https://www.ncbi.nlm.nih.gov/pubmed/19443441
http://dx.doi.org/10.1093/nar/gkp346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715230/
https://www.ncbi.nlm.nih.gov/pubmed/19443441
http://dx.doi.org/10.1093/nar/gkp346

Ejemplares similares