Cargando…

CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA

CUGBP2 (ETR-3/NAPOR/BRUNOL3) promotes inclusion of cardiac troponin T (cTNT) exon 5 via binding between positions 21 and 74 of the downstream intron. The molecular mechanism by which CUGBP2 activates cTNT exon 5 inclusion is unknown. Our results suggest that CUGBP2 promotes exon inclusion by a novel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Goo, Young-Hwa, Cooper, Thomas A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715230/ https://www.ncbi.nlm.nih.gov/pubmed/19443441 http://dx.doi.org/10.1093/nar/gkp346

Ejemplares similares

Identification of truncated forms of U1 snRNA reveals a novel RNA degradation pathway during snRNP biogenesis
por: Ishikawa, Hideaki, et al.
Publicado: (2014)

Architecture of the U6 snRNP reveals specific recognition of 3′-end processed U6 snRNA
por: Montemayor, Eric J., et al.
Publicado: (2018)

Assembly and dynamics of the U4/U6 di-snRNP by single-molecule FRET
por: Hardin, John W., et al.
Publicado: (2015)

Evidence for complex dynamics during U2 snRNP selection of the intron branchpoint
por: Kao, Ching-Yang, et al.
Publicado: (2021)

Human U1 snRNA forms a new chromatin-associated snRNP with TAF15
por: Jobert, Laure, et al.
Publicado: (2009)

Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo
por: Zhao, Xinliang, et al.
Publicado: (2007)

Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways
por: Chen, Li, et al.
Publicado: (2017)

Functionally important structural elements of U12 snRNA
por: Sikand, Kavleen, et al.
Publicado: (2011)

Structure-function analysis of the Yhc1 subunit of yeast U1 snRNP and genetic interactions of Yhc1 with Mud2, Nam8, Mud1, Tgs1, U1 snRNA, SmD3 and Prp28
por: Schwer, Beate, et al.
Publicado: (2014)

Ecd promotes U5 snRNP maturation and Prp8 stability
por: Erkelenz, Steffen, et al.
Publicado: (2021)

Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins
por: Crisci, Angela, et al.
Publicado: (2015)

A 10S galectin-3–U1 snRNP complex assembles into active spliceosomes
por: Haudek, Kevin C., et al.
Publicado: (2016)

SAM68 interaction with U1A modulates U1 snRNP recruitment and regulates mTor pre-mRNA splicing
por: Subramania, Suryasree, et al.
Publicado: (2019)

Structural requirements for protein-catalyzed annealing of U4 and U6 RNAs during di-snRNP assembly
por: Didychuk, Allison L., et al.
Publicado: (2016)

Composition and processing activity of a semi-recombinant holo U7 snRNP
por: Bucholc, Katarzyna, et al.
Publicado: (2020)

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA
por: Spiller, Michael P., et al.
Publicado: (2007)

Reconstitution of a functional 7SK snRNP
por: Brogie, John E., et al.
Publicado: (2017)

DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity
por: Duchemin, Amandine, et al.
Publicado: (2021)

Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2
por: Hogg, Rebecca, et al.
Publicado: (2014)

Genome-wide RNA-binding analysis of the trypanosome U1 snRNP proteins U1C and U1-70K reveals cis/trans-spliceosomal network
por: Preußer, Christian, et al.
Publicado: (2014)

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis
por: Leung, Adelaine K. W., et al.
Publicado: (2011)

TSSC4 is a component of U5 snRNP that promotes tri-snRNP formation
por: Klimešová, Klára, et al.
Publicado: (2021)

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing
por: McGrail, Joanne C., et al.
Publicado: (2009)

Requirements for gene silencing mediated by U1 snRNA binding to a target sequence
por: Abad, Xabi, et al.
Publicado: (2008)

LSM1 over-expression in Saccharomyces cerevisiae depletes U6 snRNA levels
por: Luhtala, Natalie, et al.
Publicado: (2009)

The U5 snRNA Internal Loop 1 Is a Platform for Brr2, Snu114 and Prp8 Protein Binding During U5 snRNP Assembly
por: Nancollis, Verity, et al.
Publicado: (2013)

Stem–loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly
por: Sharma, Shalini, et al.
Publicado: (2014)

Nuclear exchange of the U1 and U2 snRNP-specific proteins
Publicado: (1990)

The U1 snRNP-associated factor Luc7p affects 5′ splice site selection in yeast and human
por: Puig, Oscar, et al.
Publicado: (2007)

Structural and mechanistic basis for preferential deadenylation of U6 snRNA by Usb1
por: Nomura, Yuichiro, et al.
Publicado: (2018)

Binding Affinity and Cooperativity Control U2B″/snRNA/U2A′ RNP Formation
por: Williams, Sandra G., et al.
Publicado: (2014)

The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling
por: Rüegger, Stefan, et al.
Publicado: (2015)

U2 snRNP Is Required for Expression of the 3′ End of Genes
por: Koga, Mitsunori, et al.
Publicado: (2014)

The integrity of the U12 snRNA 3′ stem–loop is necessary for its overall stability
por: Norppa, Antto J, et al.
Publicado: (2021)

Reovirus μ2 protein modulates host cell alternative splicing by reducing protein levels of U5 snRNP core components
por: Boudreault, Simon, et al.
Publicado: (2022)

Negative cooperativity between Gemin2 and RNA provides insights into RNA selection and the SMN complex's release in snRNP assembly
por: Yi, Hongfei, et al.
Publicado: (2020)

Efficient transcription through an intron requires the binding of an Sm-type U1 snRNP with intact stem loop II to the splice donor
por: Alexander, Marina R., et al.
Publicado: (2010)

Use of a novel Förster resonance energy transfer method to identify locations of site-bound metal ions in the U2–U6 snRNA complex
por: Yuan, Faqing, et al.
Publicado: (2007)

Human ribosomal protein eS1 is engaged in cellular events related to processing and functioning of U11 snRNA
por: Gopanenko, Alexander V., et al.
Publicado: (2017)

The Role of the U5 snRNP in Genetic Disorders and Cancer
por: Wood, Katherine A., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_q1u1o4chijqna7l9dp4ed4mmr8