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The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair

FANCM, the most highly conserved component of the Fanconi Anaemia (FA) pathway can resolve recombination intermediates and remodel synthetic replication forks. However, it is not known if these activities are relevant to how this conserved protein activates the FA pathway and promotes DNA crosslink...

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Detalles Bibliográficos
Autores principales: Rosado, Ivan V., Niedzwiedz, Wojciech, Alpi, Arno F., Patel, Ketan J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715236/
https://www.ncbi.nlm.nih.gov/pubmed/19465393
http://dx.doi.org/10.1093/nar/gkp365