R-loops do not accumulate in transcription-defective hpr1-101 mutants: implications for the functional role of THO/TREX

To get further insight into the effect that THO/TREX and R-loops have in transcription-associated recombination and transcription, we analyzed the ability to form R-loops of hpr1-101, a THO mutation that impairs transcription and mRNP biogenesis without triggering hyper-recombination. Human AID, a c...

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Detalles Bibliográficos
Autores principales: Gómez-González, Belén, Aguilera, Andrés
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715242/
https://www.ncbi.nlm.nih.gov/pubmed/19451165
http://dx.doi.org/10.1093/nar/gkp385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715242/
https://www.ncbi.nlm.nih.gov/pubmed/19451165
http://dx.doi.org/10.1093/nar/gkp385

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