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Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays

We have developed a high-throughput protein binding microarray (PBM) assay to systematically investigate transcription regulatory protein complexes binding to DNA with varied specificity and affinity. Our approach is based on the novel coupling of total internal reflectance fluorescence (TIRF) spect...

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Detalles Bibliográficos
Autores principales: Bonham, Andrew J., Neumann, Thorsten, Tirrell, Matthew, Reich, Norbert O.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715255/
https://www.ncbi.nlm.nih.gov/pubmed/19487241
http://dx.doi.org/10.1093/nar/gkp424