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Tracking transcription factor complexes on DNA using total internal reflectance fluorescence protein binding microarrays
We have developed a high-throughput protein binding microarray (PBM) assay to systematically investigate transcription regulatory protein complexes binding to DNA with varied specificity and affinity. Our approach is based on the novel coupling of total internal reflectance fluorescence (TIRF) spect...
Autores principales: | Bonham, Andrew J., Neumann, Thorsten, Tirrell, Matthew, Reich, Norbert O. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715255/ https://www.ncbi.nlm.nih.gov/pubmed/19487241 http://dx.doi.org/10.1093/nar/gkp424 |
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