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Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles
Expressed polycistronic microRNA (miR) cassettes have useful properties that can be utilized for RNA interference (RNAi)-based gene silencing. To advance their application we generated modular trimeric anti-hepatitis B virus (HBV) Pol II cassettes encoding primary (pri)-miR-31-derived shuttles that...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715259/ https://www.ncbi.nlm.nih.gov/pubmed/19474340 http://dx.doi.org/10.1093/nar/gkp446 |