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Efficient silencing of gene expression with modular trimeric Pol II expression cassettes comprising microRNA shuttles

Expressed polycistronic microRNA (miR) cassettes have useful properties that can be utilized for RNA interference (RNAi)-based gene silencing. To advance their application we generated modular trimeric anti-hepatitis B virus (HBV) Pol II cassettes encoding primary (pri)-miR-31-derived shuttles that...

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Detalles Bibliográficos
Autores principales: Ely, Abdullah, Naidoo, Tanusha, Arbuthnot, Patrick
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715259/
https://www.ncbi.nlm.nih.gov/pubmed/19474340
http://dx.doi.org/10.1093/nar/gkp446