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PKCε-dependent potentiation of TTX-resistant Na(v)1.8 current by neurokinin-1 receptor activation in rat dorsal root ganglion neurons

BACKGROUND: Substance P (SP), which mainly exists in a subtype of small-diameter dorsal root ganglion (DRG) neurons, is an important signal molecule in pain processing in the spinal cord. Our previous results have proved the expression of SP receptor neurokinin-1 (NK-1) on DRG neurons and its intera...

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Detalles Bibliográficos
Autores principales: Cang, Chun-Lei, Zhang, Hua, Zhang, Yu-Qiu, Zhao, Zhi-Qi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715383/
https://www.ncbi.nlm.nih.gov/pubmed/19563686
http://dx.doi.org/10.1186/1744-8069-5-33