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Integrin α6Bβ4 inhibits colon cancer cell proliferation and c-Myc activity

BACKGROUND: Integrins are known to be important contributors to cancer progression. We have previously shown that the integrin β4 subunit is up-regulated in primary colon cancer. Its partner, the integrin α6 subunit, exists as two different mRNA splice variants, α6A and α6B, that differ in their cyt...

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Detalles Bibliográficos
Autores principales: Dydensborg, Anders Bondo, Teller, Inga C, Groulx, Jean-François, Basora, Nuria, Paré, Fréderic, Herring, Elizabeth, Gauthier, Rémy, Jean, Dominique, Beaulieu, Jean-François
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715428/
https://www.ncbi.nlm.nih.gov/pubmed/19586553
http://dx.doi.org/10.1186/1471-2407-9-223