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Bullatacin Triggered ABCB1-Overexpressing Cell Apoptosis via the Mitochondrial-Dependent Pathway

This paper was to explore bullatacin-mediated multidrug-resistant cell apoptosis at extremely low concentration. To investigate its precise mechanisms, the pathway of cell apoptosis induced by bullatacin was examined. Bullatacin causes an upregulation of ROS and a downregulation of ΔΨ(m) in a concen...

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Detalles Bibliográficos
Autores principales: Liang, Yong-Ju, Zhang, Xu, Dai, Chun-Ling, Zhang, Jian-Ye, Yan, Yan-Yan, Zeng, Mu-Sheng, Chen, Li-Ming, Fu, Li-Wu
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715821/
https://www.ncbi.nlm.nih.gov/pubmed/19639048
http://dx.doi.org/10.1155/2009/867123