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Dcx Re-expression Reduces Subcortical Band Heterotopia and Seizure Threshold in an Animal Model of Neuronal Migration Disorder

Disorders of neuronal migration can lead to malformations of the cerebral neocortex that greatly increase the risk of seizures. It remains untested whether malformations caused by disorders in neuronal migration can be reduced by reactivating cellular migration, and whether such repair can decrease...

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Detalles Bibliográficos
Autores principales: Manent, Jean-Bernard, Wang, Yu, Chang, YoonJeung, Paramasivam, Murugan, LoTurco, Joseph J
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715867/
https://www.ncbi.nlm.nih.gov/pubmed/19098909
http://dx.doi.org/10.1038/nm.1897