Large-scale chemical dissection of mitochondrial function

Mitochondrial oxidative phosphorylation (OXPHOS) is central to physiology and disease pathogenesis. To systematically investigate its activity and regulation, we performed a wide range of assays of OXPHOS physiology and nuclear and mitochondrial gene expression across 2490 chemical perturbations in...

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Detalles Bibliográficos
Autores principales: Wagner, Bridget K., Kitami, Toshimori, Gilbert, Tamara J., Peck, David, Ramanathan, Arvind, Schreiber, Stuart L., Golub, Todd R., Mootha, Vamsi K.
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715872/
https://www.ncbi.nlm.nih.gov/pubmed/18297058
http://dx.doi.org/10.1038/nbt1387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715872/
https://www.ncbi.nlm.nih.gov/pubmed/18297058
http://dx.doi.org/10.1038/nbt1387

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