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Utilizing Ras Signaling Pathway to Direct Selective Replication of Herpes Simplex Virus-1
Re-engineering the tropism of viruses is an attractive translational strategy for targeting cancer cells. The Ras signal transduction pathway is a central hub for a variety of pro-oncogenic events with a fundamental role in normal and neoplastic physiology. In this work we were interested in linking...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715884/ https://www.ncbi.nlm.nih.gov/pubmed/19652721 http://dx.doi.org/10.1371/journal.pone.0006514 |