Utilizing Ras Signaling Pathway to Direct Selective Replication of Herpes Simplex Virus-1

Re-engineering the tropism of viruses is an attractive translational strategy for targeting cancer cells. The Ras signal transduction pathway is a central hub for a variety of pro-oncogenic events with a fundamental role in normal and neoplastic physiology. In this work we were interested in linking...

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Detalles Bibliográficos
Autores principales: Pan, Weihong, Bodempudi, Vidya, Esfandyari, Tuba, Farassati, Faris
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715884/
https://www.ncbi.nlm.nih.gov/pubmed/19652721
http://dx.doi.org/10.1371/journal.pone.0006514

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