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Discovery of novel targets for multi-epitope vaccines: Screening of HIV-1 genomes using association rule mining

BACKGROUND: Studies have shown that in the genome of human immunodeficiency virus (HIV-1) regions responsible for interactions with the host's immune system, namely, cytotoxic T-lymphocyte (CTL) epitopes tend to cluster together in relatively conserved regions. On the other hand, "epitope-...

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Detalles Bibliográficos
Autores principales: Paul, Sinu, Piontkivska, Helen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716299/
https://www.ncbi.nlm.nih.gov/pubmed/19580659
http://dx.doi.org/10.1186/1742-4690-6-62