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Discovery of novel targets for multi-epitope vaccines: Screening of HIV-1 genomes using association rule mining
BACKGROUND: Studies have shown that in the genome of human immunodeficiency virus (HIV-1) regions responsible for interactions with the host's immune system, namely, cytotoxic T-lymphocyte (CTL) epitopes tend to cluster together in relatively conserved regions. On the other hand, "epitope-...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716299/ https://www.ncbi.nlm.nih.gov/pubmed/19580659 http://dx.doi.org/10.1186/1742-4690-6-62 |