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No association of CDK5 genetic variants with Alzheimer's disease risk

BACKGROUND: As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. METHODS: We examined genetic...

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Detalles Bibliográficos
Autores principales: Vázquez-Higuera, José Luis, Mateo, Ignacio, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Infante, Jon, Berciano, José, Combarros, Onofre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716333/
https://www.ncbi.nlm.nih.gov/pubmed/19615060
http://dx.doi.org/10.1186/1471-2350-10-68