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No association of CDK5 genetic variants with Alzheimer's disease risk
BACKGROUND: As cyclin-dependent kinase 5 (CDK5) has been implicated in the abnormal hyperphosphorylation of tau in Alzheimer's disease (AD) brain, and the development of neurofibrillary tangles, we examined the contribution of this gene to the susceptibility for AD. METHODS: We examined genetic...
Autores principales: | Vázquez-Higuera, José Luis, Mateo, Ignacio, Sánchez-Juan, Pascual, Rodríguez-Rodríguez, Eloy, Infante, Jon, Berciano, José, Combarros, Onofre |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716333/ https://www.ncbi.nlm.nih.gov/pubmed/19615060 http://dx.doi.org/10.1186/1471-2350-10-68 |
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