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Orally available Mn porphyrins with superoxide dismutase and catalase activities

Superoxide dismutase/catalase mimetics, such as salen Mn complexes and certain metalloporphyrins, catalytically neutralize reactive oxygen and nitrogen species, which have been implicated in the pathogenesis of many serious diseases. Both classes of mimetic are protective in animal models of oxidati...

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Detalles Bibliográficos
Autores principales: Rosenthal, Rosalind A., Huffman, Karl D., Fisette, Leslie W., Damphousse, Christy A., Callaway, Wyeth B., Malfroy, Bernard, Doctrow, Susan R.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716445/
https://www.ncbi.nlm.nih.gov/pubmed/19504132
http://dx.doi.org/10.1007/s00775-009-0550-4